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Therapeutic Area: Liver and Bile Duct

The purpose of this study is to evaluate the safety and efficacy of fixed dose coformulated pembrolizumab/quavonlimab (MK-1308A) plus lenvatinib in a first line (1L) hepatocellular carcinoma (HCC) setting. No hypothesis testing will be performed.

Therapeutic Area: Liver and Bile Duct

Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab in Combination With Lenvatinib in Advanced Hepatocellular Carcinoma

March 10, 2022

By Support_Clique

The purpose of this study is to evaluate the safety and efficacy of fixed dose coformulated pembrolizumab/quavonlimab (MK-1308A) plus lenvatinib in a first line (1L) hepatocellular carcinoma (HCC) setting. No hypothesis

Safety and Efficacy of Pembrolizumab Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma and Complete Radiological Response After Surgical Resection or Local Ablation

March 10, 2022

By clique_admin

This study will evaluate the safety and efficacy of pembrolizumab (MK-3475) versus placebo as adjuvant therapy in participants with hepatocellular carcinoma (HCC) and complete radiological response after surgical resection or local

Safety and Efficacy of Lenvatinib in Combination With Pembrolizumab Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma

March 10, 2022

By Tyler Kalist

The purpose of this study is to evaluate the safety and efficacy of lenvatinib (E7080/MK-7902) in combination with pembrolizumab (MK-3745) versus lenvatinib in combination with placebo as first-line therapy for the

Study of Pembrolizumab as Monotherapy in Participants With Advanced Hepatocellular Carcinoma

March 7, 2022

By Support_Clique

This is a efficacy and safety study of pembrolizumab (MK-3475, KEYTRUDA®) as monotherapy in participants with hepatocellular carcinoma (HCC) in two cohorts: participants with advanced HCC and with no curative option

Safety and Efficacy of Lenvatinib With Pembrolizumab in Combination With Transarterial Chemoembolization in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

March 7, 2022

By Tyler Kalist

The purpose of this study is to evaluate the efficacy and safety of lenvatinib and pembrolizumab in combination with TACE versus TACE plus oral and intravenous (IV) placebos in participants with

Pembrolizumab Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma

March 7, 2022

By clique_admin

This is a study of pembrolizumab plus gemcitabine/cisplatin versus placebo plus gemcitabine/cisplatin as first-line therapy in participants with advanced and/or unresectable biliary tract carcinoma. The primary hypothesis is pembrolizumab plus gemcitabine/cisplatin

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