El objetivo de este estudio es evaluar la seguridad y la eficacia de nemtabrutinib (anteriormente ARQ 531) en participantes con neoplasias hematológicas de leucemia linfocítica crónica (LLC)/linfoma linfocítico pequeño (SLL), transformación de Richter, linfoma de zona marginal (LZM), linfoma de células del manto (LCM), linfoma folicular (FL) y macroglobulinemia de Waldenström (WM).
El objetivo del estudio es determinar la seguridad y tolerabilidad de pembrolizumab/vibostolimab (MK-7684A) en neoplasias hematológicas. Este estudio también evaluará la tasa de respuesta global (ORR), la duración de la respuesta (DOR) y la tasa de control de la enfermedad (DCR) tras la administración de pembrolizumab/vibostolimab. Además, este estudio caracterizará el perfil farmacocinético (PK) de … Continued
In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).
This is a study evaluating the efficacy, safety, and pharmacokinetics of MK-1084 in participants with advanced solid tumors with identified kirsten rat sarcoma viral oncogene homolog G12C (KRASG12C) mutation and MK-1084
The goal of this study is to evaluate the efficacy and safety of pembrolizumab plus belzutifan plus lenvatinib or pembrolizumab/quavonlimab plus lenvatinib versus pembrolizumab plus lenvatinib as first-line treatment in participants
Substudy 02D is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study. The goal of
The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared with chemotherapy alone in participants with advanced/metastatic gastroesophageal cancer. The
The purpose of this study is to assess the antitumor efficacy and safety of perioperative enfortumab vedotin (EV) plus pembrolizumab and radical cystectomy (RC) + pelvic lymph node dissection (PLND) compared
Substudy 03B is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy
Substudy 03A is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy
