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Study Keyword: Programmed Cell Death 1 Ligand 1

This is a single-arm, open-label, multicenter, efficacy, and safety study of pembrolizumab in adult and pediatric participants with previously untreated advanced Merkel Cell Carcinoma (MCC). The primary objective of the trial is to assess the objective response rate, as assessed by blinded independent central review per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) modified to follow a maximum of 10 target lesions and a maximum of 5 target lesions per organ, following administration of pembrolizumab.

Study Keyword: Programmed Cell Death 1 Ligand 1

Pembrolizumab as First-line Therapy for Advanced Merkel Cell Carcinoma

March 10, 2022

By clique_admin

This is a single-arm, open-label, multicenter, efficacy, and safety study of pembrolizumab in adult and pediatric participants with previously untreated advanced Merkel Cell Carcinoma (MCC). The primary objective of the trial

A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC.

March 10, 2022

By clique_admin

This is a trial in adult participants with unresectable, locally advanced, Stage III non-small cell lung cancer (NSCLC) treated with pembrolizumab in combination with platinum doublet chemotherapy and standard thoracic radiotherapy

Estudio de pembrolizumab más docetaxel frente a placebo más docetaxel en el cáncer de próstata metastásico resistente a la castración sin quimioterapia previa

March 7, 2022

By Tyler Kalist

The purpose of this study is to assess the efficacy and safety of the combination of pembrolizumab (MK-3475) and docetaxel in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC)

Estudio de pembrolizumab más olaparib frente a acetato de abiraterona o enzalutamida en el cáncer de próstata metastásico resistente a la castración

March 7, 2022

By clique_admin

The purpose of this study is to assess the efficacy and safety of the combination of the polyadenosine 5′-diphosphoribose poly(ADP-ribose) polymerase (PARP) inhibitor olaparib and pembrolizumab in the treatment of participants

Coformulación de pembrolizumab/vibostolimab frente a la monoterapia con pembrolizumab para el cáncer de pulmón de células no pequeñas metastásico positivo al ligando de muerte celular programada 1

March 7, 2022

By Support_Clique

The primary hypotheses are that coformulated pembrolizumab/vibostolimab is superior to pembrolizumab alone with respect to (1) overall survival (OS) in participants with programmed cell death 1 ligand 1 (PD-L1) tumor proportion

Estudio de pembrolizumab en adultos con carcinoma de células escamosas cutáneo recurrente/metastásico o carcinoma de células escamosas cutáneo (cSCC) no resecable localmente avanzado

March 7, 2022

By Support_Clique

The purpose of this study is to evaluate the safety and efficacy of pembrolizumab (MK-3475) in adult participants with recurrent or metastatic(R/M) cutaneous Squamous Cell Carcinoma (cSCC) or locally advanced (LA)

Seguridad y eficacia de pembrolizumab en comparación con placebo en melanoma en estadio II de alto riesgo extirpado

March 7, 2022

By clique_admin

This 2-part study will evaluate the safety and efficacy of pembrolizumab (MK-3475) compared to placebo in participants with surgically resected high-risk Stage II melanoma. Participants in Part 1 will receive either

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