- Trials
- Breast
Investigational Clinical Trials for Breast Cancer
We’re committed to our mission of finding new treatments that may help improve the lives of people with cancer. Our clinical trials for breast cancer study investigational medications alone, or in combination with other study medications or standard of care therapy. We perform these trials to see if they can help prevent, find, or treat cancer.
For patients with hormone receptor-positive breast cancer
There are three different receptors that are commonly found in breast cancer cells: the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2). When the hormones estrogen and progesterone attach to their receptors, they are activated and fuel cancer growth. Active HER2 also fuels cancer growth. When any of these receptors are present on the cell, non-chemotherapy treatments that block these receptors, such as hormone therapy or HER2-targeted therapy, work either alone or in combination with chemotherapy to kill cancer cells or stop their growth.
For patients with triple-negative breast cancer (TNBC)
Triple-negative breast cancer represents 10% to 15% of all breast cancers. A TNBC diagnosis means that the cancer cells have tested negative for the 3 different receptors that are commonly found on breast cancer cells: the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2).
There is a lot to consider when deciding whether to participate in a clinical trial. Any clinical trial includes risks, which the study doctor will review with you. Make sure you understand the risks before participating.
About Clinical Trials
Clinical trials are scientific studies that test investigational medications to see if they’re safe and effective. Learn how a trial works and what you should consider before participating.